Microcrystalline cellulose, for thin-layer chromatography

Typical Properties
CAS	9004-34-6
Catalog	ACM9004346-30
Molecular Weight	324.28 g/mol
Melting Point	76-78 °C
Flash Point	260 °C
Density	1.5 g/cm³ at 20 °C
Appearance	White or almost white
Storage	2-30 °C
Biological Source	Synthetic
Color	White or almost white
Composition	(C6H10O5)n
Diameter	5-40 um
EC Number	232-674-9
Grade	Reagent Grade
MDL Number	MFCD00081512
pH	5-7.5 (20 °C, 100 g/L in H₂O, slurry)
Quality Level	100
Shipping	Ambient
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.

Overview

Description

Microcrystalline cellulose (MCC), mainly composed of linear polysaccharides bound by β-1,4-glucosidic bonds, is a free-flowing natural cellulose hydrolyzed by dilute acid to the limit of degree of polymerization (LODP). The very fine short rod-like or powder-like porous particles. Due to the existence of hydrogen bonds between the molecules of microcrystalline cellulose, the hydrogen bonds are associated when pressed, so it has a high degree of compressibility, and is often used as an adhesive. Microcrystalline cellulose can also be used as a sustained release agent for pharmaceuticals. In addition, MCC is also widely used in the food industry and cosmetics industry. Microcrystalline cellulose powder can form a stable dispersion system in water, and it can be combined with drugs to make cream or suspension liquid, and can also be used as capsules. Microcrystalline cellulose is gelatinized by vigorous stirring in water, and can also be used to manufacture paste and suspension type pharmaceutical preparations.

Features

Not fibrous but extremely fluid; Partial dissolution and swelling in dilute alkaline solution; High reactivity during carboxymethylation, acetylation and esterification; Has a lower degree of polymerization and a larger specific surface area

Application

Used as vascular blocking material;Used as excipient, binder and disintegrant for pharmaceutical tablets;Use as a suspending agent in liquid pharmaceutical preparations;Used as stabilizer and binder in food applications including beverages