Hydroxypropylmethylcellulose, average Mn ~120 kDa

Typical Properties
CAS	9004-65-3
Catalog	ACM9004653-11
Molecular Weight	Average Mn ~120 kDa
Melting Point	225-230 °C
Density	1.39 g/cm³
Solubility	H₂O: 50 mg/mL, clear to very faintly turbid, faintly yellow
Appearance	White to cream
Storage	Room Temp
Biological Source	Synthetic
Color	White to cream
EC Number	618-389-6
Grade	Reagent Grade
MDL Number	MFCD00131360
Mesh	100 Mesh
Quality Level	200
Shipping	Ambient
Stability	Stable. Solid is combustible, incompatible with strong oxidizing agents.
Transmittance	>98.5 %
Viscosity	100,000 cP, 2 wt. % in H₂O(20 °C, Ubbelohde)(lit.)

Overview

Description

Hydroxypropyl methylcellulose (HPMC) is a non-ionic cellulose ether made of natural polymer material cellulose through a series of etherification. It is an odorless, tasteless and nontoxic white powder that swells in cold water to a clear or slightly hazy colloidal solution. Hydroxypropyl methylcellulose is partly substituted by o-methyl group and partly substituted by o-2-hydroxypropyl group, and is divided into different grades because of different viscosity and degree of substitution. It has the characteristics of thickening, dispersing, emulsification, film-forming, suspension, adsorption, surface activity, water retention and protective colloid.

Features

Reversible gelation upon heating; Surface active and enzyme resistant; Pseudoplasticity

Application

Emulsifiers, Thickeners and Suspending Agents;For the development of controlled release drugs.;Binders, lubricants, steric stabilizers and water retention aids