Carboxyl Gold Nanorods (Diameter: 25nm)

Typical Properties

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Overview of Carboxyl Gold Nanorods (Diameter: 25nm)

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Description

Carboxyl gold nanorods are gold nanorods with carboxyl groups on their surface. They are unique in that they are elongated in shape and have a high surface area, allowing for coupling with a variety of moieties that react with carboxylic acids. In addition, they have good stability and biocompatibility. Our 25 nm diameter carboxyl gold nanorods can be easily synthesized using a variety of methods, including template, seed-mediated growth, photochemical, and electrochemical methods. The size, shape, and surface functionalization of the nanorods can be carefully controlled to tune their properties for specific applications. And they are extensively purified after synthesis, reducing contaminants during the manufacturing process that might interfere with sensitive downstream applications.

Applications

Our 25 nm diameter carboxyl gold nanorods are ideal for applications that require conjugation of proteins or other ligands to the nanorod surface using standard EDC/NHS chemistry. The 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) activates the carboxylic acid, allowing it to react with N-hydroxysuccinimide (NHS) and acquire new functionality. The introduction of the NHS group then allows it to react with primary amines, enabling covalent coupling to proteins and antibodies with exposed amine-containing residues such as lysine. This permanent attachment allows for further downstream applications, such as monitoring and localization of the now-tagged molecule within cells.

Storage

This product should be stored at 4 °C. It is stable for at least 6 months if unopened and stored as specified.

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