Encapsulation and Release

Research and Practice of Colloids in Encapsulation and Release

Over the past long time, micro- and nano-scale colloidal materials have been favored by many scientific and industrial researches, found a wide range of applications, and provided considerable advantages in use. In the field of delivery, various methods have been discovered to utilize colloidal particles to synthesize nanocapsules and microcapsules, which can be used to encapsulate and release various compounds such as drugs, nutrients, catalysts or fragrances. Utilizing modular colloidal building blocks to form capsule shells can yield unprecedented material properties that are far superior to traditional encapsulation structures.

Fig.1 Overview of utilized routes for the formation of colloidal capsules.^[1]

encapsulation efficiency, the functional properties of colloidal particles can also serve as an important reference for designing triggered release conditions. Due to the variety of functional properties of colloidal particles, specific conditions that can be engineered to trigger release are abundant, including changes in solution pH, salt concentration, light, oxygen, particle strength, enzyme activity, or temperature.

Fig.2 Schematic illustration of colloidal particles releasing encapsulated BPP through various mechanisms.^[2]

Alfa Chemistry has colloidal materials with different physicochemical properties and a variety of synthesis techniques, capable of providing various supports for encapsulation and release applications. We can provide synthetic routes for new encapsulation and release systems, or create custom functionalities for these systems. We provide expertise in designing more efficient delivery systems, advancing scientific research and market applications.

What Can We Do?

• Alfa Chemistry can provide a variety of colloidal products with different properties for encapsulation and release applications.
• Alfa Chemistry helps customers develop new colloid delivery systems and develop more complex structures for specific advanced applications.
• Alfa Chemistry can use computer simulations to provide useful theoretical predictions to support the rational design of colloidal encapsulation and release systems.

References

1. Bollhorst, et al. Colloidal capsules: nano- and microcapsules with colloidal particle shells. Chemical Society Reviews. 2017.
2. [1] Perry S L, Mcclements D J. Recent Advances in Encapsulation, Protection, and Oral Delivery of Bioactive Proteins and Peptides using Colloidal Systems. Molecules. 2020, 25(5).

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